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How SARS-CoV-2 reaches the brain

November 2020
Charité–Universitätsmedizin Berlin, Berlin, Germany
Using post-mortem tissue samples, the researchers have studied the mechanisms by which SARS-CoV-2 can reach the brains of patients with COVID-19, and how the immune system responds to the virus once it does. The results show that SARS-CoV-2 enters the brain via nerve cells in the olfactory mucosa. SARS-CoV-2 appears to follow neuroanatomical structures, penetrating defined neuroanatomical areas including the primary respiratory and cardiovascular control centre in the medulla oblongata.
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19
Frank L. Heppner
#434
Added on: 12-18-2020
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