Biofabrication of a multicellular hydrogel-based model of cancer cell invasion
2017
Tulane University, New Orleans, USA
The study describes the development of a model based on a hydrogel scaffold using biofabrication. Human primary adipose cells from obese or normal patients were successfully combined with human breast cancer cells lines to study the impact of obesity in cancer cell invasion. Moreover, the transparency of the hydrogels gives the opportunity to easily monitor this model using microscopic methods. This model successfully integrates two cell types in a hydrogel microenvironment that allows studying cancer cell invasion of adipose tissue.
Laser direct-write based fabrication of a spatially-defined, biomimetic construct as a potential model for breast cancer cell invasion into adipose tissue
Douglas B Chrisey
Added on: 07-31-2021
[1] https://iopscience.iop.org/article/10.1088/1758-5090/aa6bad[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
