3D hydrogel-based model of metastasis
2016
Arizona State University, Tempe, USA
A gelatin methacrylate hydrogel is used combined with photolithography to produce a tunable 3D model of human breast cancer metastasis. Using different cell lines, including human breast cancer and non-tumorigenic mammary epithelial cells, it is confirmed that this 3D platform can enhance different cell-specific behaviours, like invasive processes or cluster formation, and analyze them. Therefore, this model represents a promising development to use 3D tumor models to study human breast cancer metastasis.
A three dimensional micropatterned tumor model for breast cancer cell migration studies
Mehdi Nikkhah
Added on: 07-23-2021
[1] https://www.sciencedirect.com/science/article/abs/pii/S0142961215009497?via%3Dihub[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
