3D culture with breast cancer matrix-based scaffolds
November 2018
Inner Mongolia Hospital, Hohhot, China(1)
Inner Mongolia University, Hohhot, China(2)
Inner Mongolia University, Hohhot, China(2)
Breast cancer extracellular matrices are used as 3D culture scaffolds by decellularizing human breast cancer biopsies. When recellularizing control or diseased extracellular matrices with human breast cancer cells, breast cancer-obtained matrices induce cancer-related behaviours, whereas control samples block those same behaviours. Thus, the use of decellularized cancer-related extracellular matrices in 3D culture modelling can be a powerful tool for breast cancer preclinical research.
Decellularized breast matrix as bioactive microenvironment for in vitro three-dimensional cancer culture
Yuzhen Ma(1), Yanfeng Dai(2)
Added on: 07-20-2021
[1] https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.26782[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
