Computational prediction of key processes in tumor progression
December 2018
Duke University School of Medicine / Duke Cancer Institute, Durham, USA(1)
Rice University, Houston, USA(2)
Rice University, Houston, USA(2)
In this study, the authors focus on trying to model the epithelial-mesenchymal transition and the formation of cancer stem cells in tumor progression by using a computational simulation. Using this method, they identify a signaling pathway that shows to be important in tumor organoid formation.
Toward understanding cancer stem cell heterogeneity in the tumor microenvironment
Gayathri R. Devi(1), Herbert Levine(2), Mohit Kumar Jolly(2), José Nelson Onuchic(2)
Added on: 07-03-2021
[1] https://www.pnas.org/content/116/1/148[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
