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Tumor model platform with microvasculature for drug testing

2018
Auburn University, Auburn, USA
#cancer, #drug efficacy, #microfluidic device, #spheroid, #vascular transport
In this work, a model consisting of a bioengineered, chip-based 3D cancer model with microvasculature is developed. This new multicellular model allows the interactions of different cell types and microenvironments to be studied through the vasculature and provides a new platform for drug testing in preclinical studies.
A microvascularized tumor-mimetic platform for assessing anti-cancer drug efficacy
Elizabeth A. Lipke

Shantanu Pradhan et al. Scientific Reports 2018 [1]   URL
EURL ECVAM [2]   URL
#624
Added on: 07-02-2021
[1] https://www.nature.com/articles/s41598-018-21075-9[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
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