Nasopharyngeal carcinoma models to test the efficacy of immunotherapies
2017
Southern Medical University, Shenzhen, China
Relapse and metastasis of nasopharyngeal carcinoma are presumably attributed to cancer stem cells. In recent years, chimeric antigen receptor (CAR) modified immune effector cells have been shown to have impressive antitumour efficacy. Nasopharyngeal carcinoma models based on patients cells formed into spheroids are generated to use the efficiency of a novel immunotherapy based on CAR technology.
5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells
Kaitai Yao
Added on: 07-01-2021
[1] https://www.nature.com/articles/s41598-017-04756-9[2] https://data.jrc.ec.europa.eu/dataset/352f7dfd-05cf-434b-a96a-7e270dc76573
