Development of an improved human-skin equivalents
October 2020
RIKEN Center for Developmental Biology, Kobe, Japan
In this study, a human skin equivalent was modelled, taking into account the natural tension of the skin. Homeostatic tension is important for skin structure and functionality. The results show improved interaction of the cells with the extracellular matrix and activity of mechanotransduction signalling that relies on tension. The model presents a close resemblance to the "in vivo"- skin conditions.
Tissue-scale tensional homeostasis in skin regulates structure and physiological function
Takashi Tsuji
Added on: 11-19-2020
[1] https://www.nature.com/articles/s42003-020-01365-7[2] https://www.news-medical.net/news/20201030/Researchers-develop-new-improved-human-skin-equivalent.aspx