MRI shows brain iron accumulation in Alzheimer's patients
2020
Medical University of Graz, Graz, Austria
The authors developed a modified MRI approach to analyze the iron content in the neocortex of Alzheimer’s disease (AD) patients. The brains of 100 AD patients and 100 healthy volunteers were examined with a follow-up analysis after 17 months. Iron concentration in the deep grey matter and neocortical regions was higher in AD patients than in healthy control participants. Changes in iron levels over time in the temporal lobe were associated with cognitive decline in individuals with AD.
Cross-sectional and longitudinal assessment of brain iron level in Alzheimer disease using 3-T MRI
Reinhold Schmidt
Added on: 09-17-2020
[1] https://pubs.rsna.org/doi/10.1148/radiol.2020192541
