New method to fight cancer with molecular fibers
2020
Max Planck Institute for Polymer Research, Mainz, Germany
The study describes a modular protein polymerization platform that can form fibrillar intracellular structures, triggering apoptosis. The chemical properties of the system allow polymerization only in the presence of a highly acidic intracellular environment and a high metabolic rate, that are typical for cancer but not for healthy cells. Thus, this platform can potentially be used in advancing new cancer therapies.
Controlled supramolecular assembly inside living cells by sequential multistaged chemical reactions
David Y. W. Ng, Tanja Weil
Added on: 09-16-2020
[1] https://pubs.acs.org/doi/10.1021/jacs.0c05261?goto=supporting-info[2] https://www.bionity.com/en/news/1167911/the-web-of-death.html
