Neurotoxicity assay for the evaluation of marine biotoxins
2020
University of Konstanz, Konstanz, Germany
A microcystin assay was developed for human neurotoxicity caused by marine biotoxins. Using the data for preliminary risk assessment showed that normal ambient/environmental exposure levels are unlikely to trigger neurotoxicity, whereas higher concentrations result in reduction in cell count or neurite area.
The cells used in this assay are LUHMES (Lund human mesencephalic) as well as human peripheral neurons derived from pluripotent stem cells.
Examination of microcystin neurotoxicity using central and peripheral human neurons
Marcel Leist
Added on: 07-22-2020
[1] https://www.altex.org/index.php/altex/article/view/1751
