Differences in neurons, derived from stem cells of schizophrenia or autism patients
2019
University of Tübingen, Reutlingen, Germany
HiPSC-derived neurons from healthy control individuals
as well as from patients with schizophrenia and autism were tested in a panel of assays, including quantification of synaptic markers, measurement of neurite outgrowth, analysis of calcium signals as well as transcriptome analysis. The results are useful to discriminate autism and schizophrenia phenotypes in hiPSC-derived neurons derived from different patients.
Comparative characterization of human induced pluripotent stem cells (hiPSC) derived from patients with schizophrenia and autism
Hansjürgen Volkmer
Added on: 07-09-2020
[1] https://www.nature.com/articles/s41398-019-0517-3
