Non Animal Testing Database
EnglischDeutsch
Download XML for Micrsoft Excel
Download CSV for Microsoft Excel
Copy search query
Print / PDF

3D spheroids screening for cancer drugs identification

2018
Department of Molecular Medicine, The Scripps Research Institute, Jupiter, USA
#cancer, #drug discovery, #high throughput screening, #pancreatic cancer
The study implements a high throughput screening approach using 3D spheroids for the identification of signaling targets in oncology. The authors identify Proscillaridin A as a selective inhibitor of cells harboring a specific oncogenic allele.
A novel three-dimensional high-throughput screening approach identifies inducers of a mutant KRAS selective lethal phenotype
Joseph Kissil, Timothy Spicer

Smitha Kota et al. Oncogene 2018 [1]   URL
Technology Networks [2]   URL
#21
Added on: 04-21-2020
[1] https://www.nature.com/articles/s41388-018-0257-5[2] https://www.technologynetworks.com/cancer-research/news/3d-spheroids-help-scientists-discover-smarter-cancer-drugs-302832
Back to Top
English German
Project of


Supported by


Logo
Lush Prize Winner 2022


Lush Prize Winner 2022
Winner of the Animal Protection Prize of Lower Saxony 2022

Winner of the Animal Protection Prize of Lower Saxony 2022

Suscribe to RSS Feed Legal Notice Privacy Policy

Warning: Internet Explorer

The IE from MS no longer understands current scripting languages, the latest main version (version 11) is from 2013 and has not been further developed since 2015.

Our recommendation: Use only the latest versions of modern browsers, for example Google Chrome, Mozilla Firefox or Microsofrt Edge, because only this guarantees you sufficient protection against infections and the correct display of websites!