AI-based protein design tool in an app format
CompanyExazyme, Berlin, Germany
To predict protein evolution, the start-up company Exazyme has developed an AI-based protein design tool in an easy-to-use app format. First, a starting data set is uploaded to the app. An algorithm checks whether the data is suitable for further processing. The search or design request can then be individually configured to suit the research interest. The app enables, among other things, random mutations, digital deep mutation scans or a selection based on a fixed list of candidates. Within a few minutes, the AI provides sequence predictions for the desired properties of the protein and information on protein quality, which can then be tested immediately in the wet laboratory. To optimize the artificial enzymes, subsequent data sets can be uploaded after the tests. The program is suitable for a variety of different protein modifications such as: increasing protein catalysis and enzyme activity (for faster biochemical reactions), improving protein stability in different solvents and at certain temperatures (to improve storage, transport and distribution) or increasing the Protein affinity (for improved protein-protein interaction).
Artificial intelligence. Human ingenuity.
www.exazyme.com
Added on: 10-04-2023
[1] https://exazyme.com/
