hiPSC-based neurons for modelling neurological diseases and assessing neurotoxicities
CompanyFUJIFILM Cellular Dynamics Inc., Madison, USA
The nerve cells from FUJIFILM Cellular Dynamics Inc. (FCDI) obtained from human induced pluripotent stem cells (hiPSCs) enable the development of complex, three-dimensional mini-brain models for researching neurological processes and diseases. The iCell kits include a range of different cell types such as: astrocytes, microglia, motor neurons, retinal pigment epithelial cells, various neurotransmitter-associated nerve cells (dopa, GABA and gluta neurons), as well as a specially developed cell kit for modeling the blood-brain barrier. The iCell Blood-Brain Barrier Isogen Kit is of particular relevance for drug research as it enables the evaluation of drugs to be tested with regard to possible neurotoxicities, as well as an assessment of their permeability and their possible influence on the barrier function of the blood-brain barrier. The cell kits are suitable for modelling different diseases of the central nervous system; ranging from neurodegenerative diseases, such as Parkinson's or Alzheimer's, to neurodevelopmental diseases, such as autism spectrum disorders (ASD). FCDI offers the cryopreserved nerve cells in a healthy state and with pre-programmed diseases. The neural iCell kits are therefore suitable for a variety of (pre-)clinical applications and studies and can help to expand the understanding of neuropathological processes and improve the drug therapy of neurological diseases.
iCell iPSC neurons
www.fujifilmcdi.com
Added on: 09-21-2023
[1] https://www.fujifilmcdi.com/products/neural-cells
