Plant-based wound dressing to promote the natural wound healing process
2020
University of Helsinki, Helsinki, Finland
The present clinical study evaluates the properties of a plant-based hydrogel dressing (FibDex®) for the healing process of skin graft sites. The wound dressings were based on nanofibrillar cellulose (NFC), which is obtained from birch wood. The study included 24 patients with a mean age of 49 ± 18 years who required skin transplantation. The focus of the postoperative assessment of the healing process was the wound healing time. Furthermore, data on epithelialization, the patient's subjective perception of pain, skin elasticity, transepidermal water loss and scar appearance (using the POSAS scale) were collected. The wound dressings show high biocompatibility. NCF is able to absorb and store water and thus creates an optimal moisture balance for the wound to be healed. The dressings also have the advantage of being removed automatically after re-epithelialization, thus saving the patient painful dressing changes. The findings show that the use of the hydrogel patches effectively supports the wound healing process. In addition, the results indicate that FibDex significantly improves the elasticity of healed skin and the appearance of scars compared to polylactide-based copolymer wound dressings.
Clinical study of nanofibrillar cellulose hydrogel dressing for skin graft donor site treatment
raili.koivuniemi@helsinki.fi
Added on: 09-12-2023
[1] https://www.liebertpub.com/doi/10.1089/wound.2019.0982[2] https://www.upmbiomedicals.com/products/clinical/fibdex/
