Microelectrode array and live cell analysis systems for assay-based studies
CompanyAxion BioSystems, Inc., Atlanta, USA
Axion BioSystems microelectrode array (MEA) and live cell analysis systems (Maestro Edge and Maestro Pro) enable non-invasive, label-free measurement and visualization of cellular activities in real time. The models detect important parameters of neuronal network activity, cardiac function, and cell growth, death, and adhesion. Integrated software programs enable precise control and monitoring of the cultured microtissues. The CO2 and temperature ratio of the cell environment is regulated via “smart environment chambers”. The control of cell activity occurs through electrical stimulation or light pulses via the compatible Lumos optical stimulation system. To further fine-tune the experiments, the company offers a range of different opaque and transparent MEA cell culture plates in various well-size formats, which are equipped with low-noise recording electrodes and special stimulation electrodes. Using a “one-button setup”, the experiments can be fully automated over a period of up to several weeks and can be controlled and monitored independently of the laboratory via a compatible smartphone app. The models are suitable for neuro-, cardio- or oncological screening procedures to identify relevant active ingredients, as well as for the analysis of virological processes or the assessment of short-term and long-term cellular interactions. The Maestro systems enable the development of a variety of different assay-based studies that can help deepen the understanding of pathological processes and accelerate the target validation of promising drug candidates in drug development.
MEA
www.axionbiosystems.com
Added on: 09-06-2023
[1] https://axionbiosystems.com/products/mea
