Influence of dopamine on cognitive function
2023
Technische Universität Dresden, Dresden, Germany
The aim of this functional brain imaging study, was to investigate potential effects of a placebo-controlled L- DOPA intervention on spatial learning and memory in healthy young and older adults at the behavioral and brain level.
Functional neuroimaging was performed with187 volunteers. Participants attended three fMRI sessions, one behavioral and two pharmaco-fMRI, in which they either received L-DOPA or a placebo before performing a computerized spatial navigation task.
The results suggest that increasing dopamine availability improves hippocampus-dependent place learning in some older adults
Dopamine differentially modulates medial temporal lobe activity and behavior during spatial navigation in young and older adults
Christian Baeuchl
Added on: 04-24-2023
[1] https://www.sciencedirect.com/science/article/pii/S1053811923002458?via%3Dihub
