Organ-on-a-chip platform for cell migration, invasion and chemotaxis
2021
Izmir Institute of Technology, Izmir, Turkey
Custom-designed 3D cell-on-a-chip devices are used for the investigation of cellular migration/invasion (IC-chip) and chemotaxis (DDI-chip). The systems reveal human breast cancer cells and macrophages in a paracrine-juxtacrine loop. Comparative 3D co-culture experiments showed that breast cancer cells changed their multicellular organization in the presence of macrophages.
Breast cancer cells and macrophages in a paracrine-juxtacrine loop
Devrim Pesen-Okvur
Added on: 12-21-2022
[1] https://www.sciencedirect.com/science/article/abs/pii/S014296122030658X
