Vasularized Micro-Brain Platform
CompanyAracari Biosciences, Irvine, USA
When treating patients, most therapeutics are delivered through the blood vessels. In Aracari’s platforms, self-assembled human blood vessels not only support tissue growth through delivery of nutrients, but also deliver drugs and cell therapies. The Vascularized Micro-Brain platform is designed to test therapeutic permeability across the blood-brain barrier. The system includes human endothelial cells, human stromal and glial cells, and enrichment of blood-brain barrier genes. Further services include physiological delivery of drugs across the barrier, tissue toxicities in the brain stromal compartment, tissue extraction for qRT-PCR and bulk or single-cell RNA seq. Aracari’s vascularized microphysiological systems provide relevant, physiological data for accelerating drug development.
Vascularized micro-brain (VMB™)
info@aracaribio.com
Added on: 12-19-2022
[1] https://aracaribio.com/technology/#vmb
