Bioengineered liquid cornea
CompanyPandorum Internationa Inc., San Carlos, USA(1)
Pandorum Technologies Pvt. Ltd., Bangalore, India(2)
Pandorum Technologies Pvt. Ltd., Bangalore, India(2)
The hydrogel formulation of the liquid cornea of the company Pandorum has 3 major components. Two biopolymers undergo a photoactive mediated transition from the liquid phase to a hydrogel or semi-solid phase, where they take the exact shape to perfectly fill in a wound site. The composition is biomimetic in terms of light transmittance and provides adequate mechanical support. The bioengineered liquid cornea is a regenerative treatment and the biopolymer acts as a sacrificial matrix for accelerating the growth of host tissue to cover the wound site. The trigger for this growth is provided by a bioactive component, the exosomes which are delivered to the wound site and embedded in the biopolymeric matrix. These exosomes are derived from the population of predominant cell types in the cornea and are programmed to promote scarless wound healing, to restore vision, the primary function of the cornea and eye.
Bioengineered Liquid Cornea
www.pandorum.com(1, 2)
Added on: 12-14-2022
[1] https://pandorum.com/bioengineered-cornea/
