Ex vivo effects of green tea compound on cancer patients immune cells
2014
Al-Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia
Green tea contains polyphenols, particularly catechins, the most abundant of which is Epigallocatechin-3-gallate (EGCG) which has been reported to exert in vitro antitumor effects in various types of cancers. In the present study, the researchers investigated the effect of the EGCG on the proliferation and capacity to secrete cytokines of immune cells isolated from cancer patients. EGCG significantly suppressed the proliferation of immune cells and cytokine secretion. Such observations may contradict the use of EGCG in cancer immunotherapy, and suggests that further studies on its use as an immunomodulatory agent in autoimmune diseases and tissue transplantation are needed.
Analysis of the effect of the active compound of green tea (EGCG) on the proliferation of peripheral blood mononuclear cells
Farid Saleh
Added on: 09-14-2021
[1] http://www.biomedcentral.com/1472-6882/14/322[2] https://data.jrc.ec.europa.eu/dataset/352f7dfd-05cf-434b-a96a-7e270dc76573
