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Affinity-based drug delivery with hydrogel

2017
Leiden University, Leiden, Netherlands
#breast cancer, #cancer therapy, #drug delivery, #hydrogel
The study describes the design and production of a drug delivery scaffold based on hydrogels. All the gels are stable for more than 25 days and have tunable gelation times. Additionally, the hydrogels can efficiently deliver doxorubicin for over 7 days in a constant manner. Also, in cell viability tests, these hydrogels show to be biocompatible and deliver doxorubicin to human breast cancer cells. Overall, this system can be an important advance in drug delivery strategies.
Dual-crosslinked human serum albumin-polymer hydrogels for affinity-based drug delivery
Roxanne E Kieltyka

Willem EM Noteborn et al. Macromolecular Materials and Engineering 2017 [1]   URL
EURL ECVAM [2]   URL
#752
Added on: 07-29-2021
[1] https://onlinelibrary.wiley.com/doi/abs/10.1002/mame.201700243[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
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