In silico analysis of estrogen receptor alpha signaling pathway
October 2016
National University of Science and Technology, Islamabad, Pakistan
The construction of a discrete model is described to analyse the behaviour of estrogen receptor alpha-associated signalling pathways to understand some of the mechanisms that lead to breast cancer metastasis. The model was able to determine gene-gene interactions of different receptors that lead to inhibition of tumour suppressor genes, giving new insights to direct further research in the treatment of human breast cancer therapies.
Formal modeling and analysis of ER-α associated Biological Regulatory Network in breast cancer
Rumeza Hanif, Samra Khalid
Added on: 07-29-2021
[1] https://peerj.com/articles/2542/[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
