Potential importance of B cells in immune response tested ex vivo in patients' tissues
2019
University of Cologne, Cologne, Germany
The composition and function of B lymphocytes, crucial players in cancer immune response, in head and neck squamous cell carcinoma (HNSCC) has not been well described yet. In the present study, the researchers analyzed B cell subsets from donor tissues by flow cytometry. Also, the humoral immune responses were analyzed in vitro against different tumor-associated antigens (TAA). In view of the increasing use of immunotherapeutic approaches, it will be important to include B cells in comprehensive phenotypic and functional analyses of tumor-associated lymphocytes.
Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma
Dirk Beutner
Added on: 07-29-2021
[1] https://www.tandfonline.com/doi/full/10.1080/2162402X.2018.1535293[2] https://data.jrc.ec.europa.eu/dataset/352f7dfd-05cf-434b-a96a-7e270dc76573
