Mathematical model to assess a combination of cancer therapies
2017
Winthrop University, Rock Hill, USA
A recent theory for tumor growth suggests that a small population of cancerous cells known as cancer stem cells have stem cell-like qualities. In the present study, the researchers developed a mathematical model of the effectiveness of immunotherapy and chemotherapy for the treatment of tumor cells and cancer stem cells. The researchers present conditions on treatment parameters to guarantee a globally attracting tumor clearance state. Further work on this model could incorporate healthy cells and monitor the detrimental effect chemotherapy has on the overall health of a patient. Also in the future, an updated model could consider different submodels for possible cancer persistent states or other specific chemotherapy and immunotherapy agents.
Global dynamics of a colorectal cancer treatment model with cancer stem cells
Kristen Abernathy
Added on: 07-27-2021
[1] https://www.sciencedirect.com/science/article/pii/S2405844016315997[2] https://data.jrc.ec.europa.eu/dataset/352f7dfd-05cf-434b-a96a-7e270dc76573
