New immunotoxin design for potential treatment of breast cancer
2015
University of Notre Dame, Notre Dame, USA
Immunotoxins constitute a new type of cancer treatment. They are chimeric proteins comprising a specific cellular targeting domain linked to a cytotoxic factor. In the present study, the researchers designed, synthesized and used in vitro a novel immunotoxin with selective cytotoxic activity on ErbB2 positive cells, a marker overexpressed in the tumor cells of approximately 30% of breast cancer patients.
Design and evaluation of a peptide-based immunotoxin for breast cancer therapeutics
Shaun W. Lee
Added on: 07-27-2021
[1] https://febs.onlinelibrary.wiley.com/doi/full/10.1016/j.fob.2015.03.005[2] https://data.jrc.ec.europa.eu/dataset/352f7dfd-05cf-434b-a96a-7e270dc76573
