Development of 3D printed scaffolds for breast cancer stem cell models
October 2018
University of Girona, Girona, Spain
Standardisation of a printing protocol for polylactic acid scaffolds is described to optimise human breast cancer stem cell culture. After trying several configurations of Fused Filament Fabrication 3D printer, the researchers found that it was possible to have higher proliferation and enhanced populations of ALDH+ cells compared to classical 2D monolayer cultures, having a more physiologically accurate microenvironment to the "in vivo" standards. The results show that this new approach could be a good tool to culture human breast cancer stem cells.
Screening of additive manufactured scaffolds designs for triple negative breast cancer 3D cell culture and stem-like expansion
Joaquim Ciurana, Teresa Puig
Added on: 07-27-2021
[1] https://www.mdpi.com/1422-0067/19/10/3148[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
