Fibroblasts facilitate permeability of an in vitro blood-brain barrier
2014
Yonsei University College of Medicine, Seoul, South Korea
To study the importance of fibroblasts in brain metastasis, several assays in several models are used. Also, two new 3D models are developed with human cells to study the permeability of a multicellular in vitro blood-brain barrier, transmigration and breast cancer cell colony formation. These new devices provide mechanistic insights into cancer-associated fibroblasts in breast cancer brain metastasis.
Cancer-associated fibroblast promote transmigration through endothelial brain cells in three-dimensional in vitro models
Nam Hoon Cho
Added on: 07-16-2021
[1] https://onlinelibrary.wiley.com/doi/10.1002/ijc.28848[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
