Non Animal Testing Database

Comparison between 2D and 3D models of breast cancer

New Mexico State University, Las Cruces, USA
The study describes the development of a hydrogel-based 3D model of breast cancer. A comparison between this 3D model and traditional 2D monolayer cultures show that the morphometric characteristics of human breast cancer cells in 3D conditions recapitulate more accurately these in "in vivo" conditions. Several imaging techniques confirm the potential of using this model for drug testing.
Morphometric analysis of a triple negative breast cancer cell line in hydrogel and monolayer culture environments
Elba E Serrano
Added on: 07-14-2021
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