Non Animal Testing Database

Mathematical and experimental approaches to improve electrochemotherapy treatments

University of Padova, Padua, Italy
Through mathematical modelling of different needle spacing, it is shown that grid electrodes can be improved for electrochemotherapy to improve coverage of the treatment area. After finding the optimal distance and voltage, the researchers confirmed in a model of human breast cancer that these parameters allow for more homogeneous electroporation. Finally, it is confirmed that computational models and experimental procedures can be used to adjust the grid electrode's configuration.
Effect of electrode distance in grid electrode: numerical models and in vitro tests
Elisabetta Sieni
Added on: 07-12-2021
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