Non Animal Testing Database
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Regular caffeine consumption affects brain structure

2021
University of Basel, Basel, Switzerland
#brain, #fMRI
In this double-blind, randomized, cross-over study, the authors examined the impact of 10-day caffeine on human grey matter volumes by fMRI in 20 habitual caffeine consumers, compared with 10-day placebo. A significant reduction in grey matter volume in the medial temporal lobe was detected after 10 days of caffeine intake compared with 10 days of placebo. However, the data do not suggest a link between sleep depth during daily caffeine intake and changes in brain morphology. In conclusion, daily caffeine intake might induce neural plasticity depending on individual metabolic processes.
Daily caffeine intake induces concentration-dependent medial temporal plasticity in humans: a multimodal double-blind randomized controlled trial
Christian Cajochen
#582
Added on: 05-11-2021
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