3D printing for advanced tissue fabrication
2021
Carnegie Mellon University, Pittsburgh, USA
The Freeform Reversible Embedding of Suspended Hydrogels (FRESH) 3D bioprinting approach was used to generate complex 3D tissue and organ models with high cell viability using a wide range of biocompatible materials. The FRESH technique enables complex tissue fabrication by using a support bath that holds the printed materials or bioinks in place until they are cured. Using this method, researchers have demonstrated that large-scale 3D bioprinting of soft tissues and other complex tissue scaffolds with properties comparable to human tissues and organs is possible. This work is opening new avenues for tissue engineering and has already produced several research advancements, including the printing of organ models from patient-specific medical images and the development of a beating cardiac tissue, which has a potential application in surgical training.
Emergence of FRESH 3D printing as a platform for advanced tissue biofabrication
Adam W. Feinberg
Daniel J. Shiwarski et al. APL Bioengineering 2021 [1]
Physicians Committee for Responsible Medicine [2]
Added on: 03-18-2021
[1] https://aip.scitation.org/doi/10.1063/5.0032777[2] https://www.pcrm.org/news/ethical-science/3d-printing-paves-way-advanced-tissue-fabrication?emci=deff8ab0-5b78-eb11-85aa-00155d43c992&emdi=356cd864-e679-eb11-85aa-00155d43c992&ceid=2015591
