VISION - an in vitro- and in silico inhalation toxicology analysis platform
2020
Fraunhofer IBMT, Sulzbach, Germany(1)
Universität des Saarlandes, Homburg, Germany(2)
Universität des Saarlandes, Homburg, Germany(2)
The research project "VISION" aims to develop and validate an in-vitro/in-silico analysis platform for inhalation toxicology studies. The platform combines a microfluidic organ culture system, more precisely an in vitro lung-liver model, and bioinformatic analyses of disease mechanisms. The in vitro systems will be developed to simulate the lung barrier and the metabolism process in the liver and, with their integration into microfluidic systems, will be used to determine specific effects of pollutants or therapeutic agents after pulmonary uptake. Using these methods, well-founded data sets will be generated as a basis for the development of the in-silico model.
VISION – Ein mikrofluidisches Chipsystem als Alternative zu Tierversuchen
Heiko Zimmermann(1), Robert Bals(2)
Added on: 10-16-2020
[1] https://www.ibmt.fraunhofer.de/de/ibmt-presse-uebersicht-2020/presse-BMBF-Vision-2020-07-13.html
