SkinEthic RHE as a test system for skin irritation
Regulatory accepted 2008
European Union Reference Laboratory for Alternatives to Animal Testing, Ispra, Italy
The SkinEthic™ Skin Irritation Test is designed for the prediction of acute skin irritation potential of chemicals by measurement of their cytotoxic effect, as reflected by MTT assay, on the Reconstructed Human Epidermis (RHE).
Validated and regulatory approved under TM2008-02 (EU) by EURL ECVAM (TSAR list), OECD Test No. 439.
Skinethic Skin Irritation Test-42bis
EURL ECVAM
Added on: 07-02-2020
[1] https://tsar.jrc.ec.europa.eu/test-method/tm2008-02[2] https://www.oecd-ilibrary.org/environment/test-no-439-in-vitro-skin-irritation-reconstructed-human-epidermis-test-method_9789264242845-en
