Skin-on-chip model for dermatological and oncological exposure and drug studies
CompanyReact4Life, Genova, Italy
React4Life's skin-on-chip technology enables the study of skin reactions to certain stimuli, active ingredients and environmental factors under controlled exposure conditions. The three-dimensionally cultured mini skin cells recapitulate the structural and functional properties of human skin in vitro and can be used in various dermatological and oncological studies. The chip platform is suitable for researching the wound healing process of the skin after mechanical injuries or for evaluating cell damage caused by long-term UV irradiation. Furthermore, the development of skin diseases such as psoriasis, eczema or skin cancer can be simulated, and their progression can be analysed. Subsequently, the microfluidic models are suitable for efficacy testing in drug development, as well as the evaluation of possible drug-induced side effects and the identification of skin-damaging toxins. In summary, the skin-on-chip model is a versatile tool for gaining a better understanding of certain mechanisms of the skin and skin diseases and can help to accelerate the development of suitable drugs.
Skin-on-Chip
www.react4life.com
Added on: 10-24-2023
[1] https://www.react4life.com/skin-on-chip/
