Microfluidic neuron-on-chip models for drug and drug discovery
CompanyNETRI, Lyon, France
The company NETRI has developed the Neuro-FluidicsTM Line for improved target validation and drug development against neurological diseases. The product line includes 6 Neuron-on-Chip platforms with 4 different architecture types. The microfluidic models combine two different technologies in a single chip and enable controlled cultivation of 2-3 co-cultures in separate compartments. All products are based on the so-called NeoBento technology, a 96-well microculture plate that is compatible with common liquid handling devices and imaging processes. 3 models (DuaLink, DuaLink Shift and TriaLink) are combined with a special micro-tunnel technology that allows for improved fluidic isolation and discontinuous connectivity between cell compartments. The other three chip models (DuaLink Ultra, TriaLink Ultra, and DuaLink Delta Ultra) have integrated microgroove technology that achieves improved axonal projection rate and continuous connectivity between co-cultures. The neuron-on-chip models are suitable for a variety of different preclinical studies and can help to expand the understanding of neuronal activities and their interactions in health and disease.
NeuroFluidics™ Line
contact@netri.com
Added on: 08-29-2023
[1] https://netri.com/netri-devices/products/neurofluidics-line/
