Deep brain stimulation for treatment of Alzheimer´s disease
December 2022
Charité – Universitätsmedizin Berlin, Berlin, Germany
Within this study, deep brain stimulation (DBS) is examined as an investigational treatment for patients with mild Alzheimer’s disease. In particular, the electrode placement was investigated and optimized with regard to the improvement of the cognitive function of the involved patients.
To investigate this, data obtained from 46 patients treated with DBS at seven international centres were used. The optimal stimulation site was identified using structural and functional connectivity data, as well as modulation of brain networks related to memory.
Findings were robust and could define an optimal target for Alzheimer’s Disease treatment that could refine DBS surgery and programming.
Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer’s disease
Andreas Horn
Added on: 01-06-2023
[1] https://www.nature.com/articles/s41467-022-34510-3
