Genomic interaction networks to identify key cancer cell line characteristics
2021
Maastricht University, Maastricht, Netherlands
Characterisation of the epigenome and transcriptome is critical for understanding the behaviour of cancer cell lines, not only for a better understanding of cancer-related processes but also for future treatments and cancer drug development. Here, the Cancer Cell Line Encyclopaedia (CCLE) 2019 identified potential candidate genes that characterise lymphoid neoplasm-type cancer cell lines. The current findings show that although B- and T-cell lymphomas are thought to differ, they may share similar genomic alterations. These key alterations are important to study and better understand the development and progression of lymphoid neoplasms.
From multi‑omics integration towards novel genomic interaction networks to identify key cancer cell line characteristics
T. J. M. Kuijpers
Added on: 02-15-2022
[1] https://www.nature.com/articles/s41598-021-90047-3
