In vitro inhalation testing
CompanyVITO NV, Mol, Belgium
To assess the toxicological potential or efficacy of inhalable substances for humans, the company VITO uses the so-called "air-liquid interface" exposure method (ALI). Here, lung cells are grown on a membrane, supplied with a cell culture medium at the bottom and exposed to airborne substances (e.g. drugs, vaccines, chemicals, nanoparticles) at the top.
VITO has a range of ALI exposure modules and aerosol generation systems (for dry powders and liquids) as well as measurement equipment for characterisation. Several different lung cell systems (mono- and co-culture cell lines as well as lung cells from human donors) are used. In addition, various options for dose determination and endpoint measurement are available.
www.vito.be
Added on: 11-17-2021
[1] https://vito.be/en/product/vitro-inhalation-testing
