Non Animal Testing Database

3D InSight Liver model for DILI predictions

InSphero AG, Schlieren, Switzerland
With 3D InSight Liver Human Microtissues, InSphero offers a turnkey screening solution for the identification of hepatotoxic substances. The tissue is produced from primary liver cells from a pool of female and male donors in coculture with Kupffer and liver endothelial cells. In microtitre plates, the cultures are viable for at least 28 days. Due to the high throughput capability and twice the sensitivity for DILI (drug-induced liver injury) predictions compared to conventional 2D hepatocytes, these models are ideal for testing drug safety and efficacy, as well as for studying healthy and diseased liver function.
Added on: 11-16-2021
Back to Top
English German
Lush Prize Winner 2022Lush Prize Winner 2022
Winner of the Animal Protection Prize of Lower Saxony 2022Winner of the Animal Protection Prize of Lower Saxony 2022

Warning: Internet Explorer

The IE from MS no longer understands current scripting languages, the latest main version (version 11) is from 2013 and has not been further developed since 2015.

Our recommendation: Use only the latest versions of modern browsers, for example Google Chrome, Mozilla Firefox or Microsofrt Edge, because only this guarantees you sufficient protection against infections and the correct display of websites!