"ID";"Original Title";"Title";"Summary";"Contact";"Citation";"URL Scientific Article";"More References";"Keywords";"Field of Research";"Method/Model";"Year of Publication";"Month of Publication";"Date of Editing"; "1122";"Data of a fluorescent imaging-based analysis of anti-cancer drug effects on three-dimensional cultures of breast cancer cells";"Development of a 3D breast cancer culture platform for drug screening";"3D models are emerging as dynamic models with high value to study cell growth and proliferation. Nowadays, coupled 3D modelling and imaging techniques offer easy-to-use systems. To study anti-cancer drugs, a simple visualization setup to image non-proliferative cells is needed. Here, a fluorescent-based assay is used to analyze cell proliferation of human breast cancer cells in a 3D model using a pulse-labelling technique with protein Kaede. The results show that it was possible to analyze the effects of 5-fluorouracil and PD0332991 anti-cancer drugs in human breast cancer cells. Overall, the researchers present a newly developed platform to easily study anti-cancer drug effects on cell proliferation to be able to do fast drug screening assays in human cells cultured in 3D conditions.";"Junji Itou, Kyoto University, Kyoto, Japan";"Junji Itou et al. Data in Brief 2015";"https://www.sciencedirect.com/science/article/pii/S2352340915002310";"EURL ECVAM, https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38";"cancer cells, breast cancer, drug screening, imaging methods, fluorescence, 3D model, cell proliferation";"Andrology, Gynaecology, Drug development and testing, Method development, Oncology";"Cell culture, Tissue models, Organoids, Spheroids, (Bio-)Assays";"2015";"10";"2021-10-31 18:04:08";