Non Animal Testing Database

Drug test in 3D model shows new insights in cancer stem cell response

Boston University, Boston, USA
Two chemotherapeutic agents (Paclitaxel and Cisplatin) show differential responses in three different human breast cancer models. The different dynamics in the three different models give key insights into the mechanisms of these drugs and the cancer stem cell responses. Overall, the 3D multicellular model is has a great potential to recreate the different interactions and dynamics in human breast tumor microenvironments in vitro .
Breast cancer spheroids reveal a differential cancer stem cell response to chemotherapeutic treatment
Mark W Grinstaff, Muhammad H Zaman
Added on: 07-14-2021
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