Non Animal Testing Database

Distinction between healthy and leukemic blood stem cells

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany(1)
The Barcelona Institute of Science and Technology, Barcelona, Spain(2)
#blood, #leukemia
By using single-cell multi-OMICS approaches, the researchers could distinguish between leukemic stem cells and healthy hematopoietic stem cells obtained from acute myeloid leukemia (AML) patients. This approach enables the identification of cancer-specific gene expression programs and the characterization of differentiation blocks induced by leukemic mutations.
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics
Lars M. Steinmetz(1), Lars Velten(2)
Added on: 05-11-2021
Back to Top
English German

Warning: Internet Explorer

The IE from MS no longer understands current scripting languages, the latest main version (version 11) is from 2013 and has not been further developed since 2015.

Our recommendation: Use only the latest versions of modern browsers, for example Google Chrome, Mozilla Firefox or Microsofrt Edge, because only this guarantees you sufficient protection against infections and the correct display of websites!