Fabrication of 3D organ models devoid of animal components
Technische Universität Berlin, Berlin, Germany
Bioprinting is a rapidly developing technology that enables the exact positioning of living cells embedded in biomaterials in precise spatial arrangements to fabricate engineered tissues and organs. While the ultimate goal of bioprinting approaches is to produce organs for transplantation purposes, bioprinted organ models also hold great potential for research purposes to serve as alternatives to animal experiments. However, standard bioprinting procedures currently use numerous hidden animal components.
This review introduces the potential of strategies to replace animal components currently included in standard procedures of bioprinting. These approaches comprise the adaptation of cells to FBS-free media, the use of bioinks composed of synthetic or plant material, and the replacement of animal components by materials of human origin which is then referred to as clean bioprinting.
Clean Bioprinting - Fabrication of 3D organ models devoid of animal components
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