Non Animal Testing Database

EpiDerm: 3D human skin model for drug and toxicity testing

validierte Methode
MatTek Corporation, Ashland, USA
MatTek’s EpiDerm is a ready-to-use, highly differentiated 3D tissue model consisting of normal, human-derived epidermal keratinocytes. Cultured at the air-liquid interface, EpiDerm allows for the evaluation of topically applied compounds, chemicals, pharmaceutical and cosmetic/personal care product ingredients and final formulations. Suitable for skin irritation and corrosion testing, as well as for the assessment of the skin irritation potential of extracts of medical devices (ISO 10993). Validated and regulatory accepted under TM2008-01 (EU) and TM1998-03 (EU) by EURL ECVAM (TSAR list), OECD test No. 431 and 439.
In vitro skin irritation and corrosion: reconstructed human epidermis (RHE) test method
Added on: 07-13-2020
Back to Top
English German

Warning: Internet Explorer

The IE from MS no longer understands current scripting languages, the latest main version (version 11) is from 2013 and has not been further developed since 2015.

Our recommendation: Use only the latest versions of modern browsers, for example Google Chrome, Mozilla Firefox or Microsofrt Edge, because only this guarantees you sufficient protection against infections and the correct display of websites!