Non Animal Testing Database

Peptide assay for detection of sensitizing chemicals

validierte Methode
European Union Reference Laboratory for Alternatives to Animal Testing, Ispra, Italy
The DPRA supports the discrimination between sensitizing and non-sensitizing chemicals. It measures in chemico the binding of test chemicals to model synthetic peptides. In skin proteins, many amino acids contain electron-rich groups capable of reacting with sensitizers. Therefore, these peptides are used by the assay so they can react with electrophilic chemicals (skin sensitizers). Validated and regulatory approved under TM2009-06 (EU) by EURL ECVAM (TSAR list), OECD Test No. 442C.
Direct Peptide Reactivity Assay
Added on: 07-03-2020
Back to Top
English German

Warning: Internet Explorer

The IE from MS no longer understands current scripting languages, the latest main version (version 11) is from 2013 and has not been further developed since 2015.

Our recommendation: Use only the latest versions of modern browsers, for example Google Chrome, Mozilla Firefox or Microsofrt Edge, because only this guarantees you sufficient protection against infections and the correct display of websites!