In-vitro canine skin
2024
Fraunhofer Institute for Interfacial Engineering and Biotechnology, Stuttgart, Germany
In this project, an in-vitro canine skin equivalent was developed to facilitate the testing of veterinary therapeutics and care products. The researchers used skin samples obtained from medically necessary surgeries, which were provided by veterinary clinics, as a starting material. From these tissue samples, keratinocytes and fibroblasts were isolated and immortalized, allowing the cells to proliferate indefinitely. The immortalized cells were then assembled into a 3D-skin model that replicates the layers of natural skin, including the epidermis and dermis.
With the canine skin model, veterinary pharmaceuticals and care products can be tested. Additionally, studies on transdermal drug delivery and skin penetration are possible.
Lab-grown canine skin provides a canvas for testing medical treatments
Anke Burger-Kentischer
Added on: 05-23-2024
[1] https://www.igb.fraunhofer.de/en/press-media/press-releases/2024/lab-grown-canine-skin-provides-a-canvas-for-testing-medical-treatments.html
