Non Animal Testing Database

Computational tool to design a handmade pulmonary valve to treat congenital heart disease

National Cheng Kung University Hospital, Tainan, Taiwan(1)
National Chin-Yi University of Technology, Taichung, Taiwan(2)
Patients with congenital heart disease may be treated with percutaneous pulmonary valve implantation to treat narrowed or leaky pulmonary valves. However, commercial options are not always available for children or special subjects. Over the years, the handmade pulmonary valved conduit has provided a strategy to customize the size to the specifications of the patient. In the present study, the researchers aimed at improving the design by generating a meta-learning-based intelligent model to train the physician to determine optimal parameters for customized valve reconstruction. This model can overcome problems arising from empirical parameter determination. The customized handmade pulmonary valved conduit produced thanks to the model were validated in vitro by assessing the regurgitation fraction and the heart pump efficiency using a circulation loop system.
Customized handmade pulmonary valved conduit reconstruction for children and adult patients using meta-learning based intelligent model
Chung-Dann Kan(1), Chia-Hung Lin(2)
Added on: 12-03-2021
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