New assay to elucidate cancer cell migration mechanisms
2014
McGill University, Montreal, Canada
A cost-effective assay is developed to study the role of extracellular matrix proteins in cancer cell migration. The assay allows the visualisation of different migration patterns depending on the extracellular matrix proteins used. Different human cancer cell lines are used separately in 2D monolayer culture to validate this assay. The results show that collagen is a promoter of cell migration in all lines without affecting proliferation. This new assay shows to be a promising and approachable assay to study cell migration "in vitro".
Ring cell migration assay identifies distinct effects of extracellular matrix proteins on cancer cell migration
Josephine Nalbantoglu
Added on: 07-27-2021
[1] https://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-7-183[2] https://data.jrc.ec.europa.eu/dataset/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
